Which growth factor is considered a biological mediator for regeneration?

Platelet-derived growth factor (PDGF) is a crucial biological mediator in the process of regeneration, particularly in the context of periodontal healing and tissue regeneration. PDGF plays a significant role in the proliferation and migration of cells involved in the healing process, such as fibroblasts and endothelial cells, which are necessary for the formation of new tissue and blood vessels.

The role of PDGF in regeneration extends to its influence on various cellular functions. It not only stimulates the proliferation of mesenchymal cells but also promotes the synthesis of extracellular matrix components, which are vital for tissue structure and integrity. Additionally, PDGF is involved in angiogenesis, the formation of new blood vessels, which is essential for providing nutrients and oxygen to the regenerating tissue.

In the context of periodontal diseases and regenerative therapies, the application of PDGF has shown promising results in enhancing healing and regeneration in periodontal tissues affected by diseases. This activity positions PDGF prominently as a biologically active factor that facilitates and mediates regeneration.

The other options represent different biological entities and mechanisms. Adipose-derived stem cells are stem cells with regenerative potential but do not strictly function as mediators in the same context as PDGF. Corneal epithelial cells are specific to the eye and focus on ocular