Which side effect is commonly associated with cyclosporin?

Gingival hyperplasia is a well-documented side effect of cyclosporin therapy. Cyclosporin is an immunosuppressant that is often used to prevent organ rejection in transplant patients and for certain autoimmune diseases. One of the notable side effects of cyclosporin is its impact on the gingival tissues.

Patients taking cyclosporin may experience an overgrowth of gum tissue, leading to gingival hyperplasia. This condition manifests as enlarged, swollen gums that can cover the teeth and cause discomfort. The mechanism behind this side effect is thought to be related to the drug's effects on the fibroblasts in the gingival tissue, promoting excess collagen production.

The presence of gingival hyperplasia in patients using cyclosporin requires careful dental management. Regular dental check-ups and good oral hygiene practices are crucial for patients on cyclosporin to mitigate the severity of this condition and maintain oral health.

Other options listed, while they may be associated with various medications or conditions, do not share the same strong correlation with cyclosporin as gingival hyperplasia does.